Bazı topikal otik solüsyonların antibakteriyel aktivitesinin değerlendirilmesi
Harun Üçüncü, A. Esin Aktaş, Halil Yazgı, Nimet Yiğit, Bülent Aktan, Yavuz Sütbeyaz
FREE FULL TEXT Anahtar Kelimeler: Uygulama, topikal; antibakteriyel ajan;bakteriyel enfeksiyon/ilaç tedavisi; otitis eksterna; otitismedia/ilaç tedavisi; Proteus mirabilis/ilaç etkisi; Pseudomonasaeruginosa/ilaç etkisi; Staphylococcus aureus/ilaçetkisi.
Assessment of antibacterial activity of some topical otological solutions
Harun Üçüncü, A. Esin Aktaş, Halil Yazgı, Nimet Yiğit, Bülent Aktan, Yavuz Sütbeyaz
Objectives: Otological solutions have long been used in the treatment of the bacterial and fungal infections of the ear. We investigated antibacterial activity of some otic solutions against the most common bacteria isolated from discharging ears. Study Design: Three solutions were used (Castellani’s, Burrow’s, and 2% salicyl alcohol) for 20 fresh isolates of each of the following organisms: Staphylococcus aureus, Proteus mirabilis, Pseudomonas aeruginosa, Escherichia coli, and Enterobacter spp.. The activity of each solution was determined by the size of the zone of inhibition of bacterial growth. Results: The Castellani’s solution showed significantly larger average inhibition zones than the other solutions did (p<0.001). Conclusion: The Castellani’s solution may be considered a good option against bacterial or mixed infections (bacterial and fungal) of the ear. Key words: Administration, topical; anti-bacterial agents;bacterial infections/drug therapy; otitis externa; otitismedia/drug therapy; Proteus mirabilis/drug effects;Pseudomonas aeruginosa/drug effects; Staphylococcusaureus/drug effects.
Harun Üçüncü, A. Esin Aktaş, Halil Yazgı, Nimet Yiğit, Bülent Aktan, Yavuz Sütbeyaz. Assessment of antibacterial activity of some topical otological solutions. Kulak Burun Bogaz Ihtis Derg. 2005; 14(3): 97-100
Corresponding Author: Harun Üçüncü |